Each 1 gram of DIPROTOP Ointment contains 0.64 mg Betamethasone dipropionate (equivalent to 0.5 mg Betamethasone) in a base containing of propylene glycol monostearate, propylene glycol, white wax and white petrolatum

ACTIONS: DIPROTOP Ointment is effective because of its anti-inflammatory, antipruritic and vasoconstrictive actions. The glycol ointment vehicle increase penetration and enhances the local effectiveness of the betamethasone dipropionate.

INDICATIONS AND USAGE: DIPROTOP Ointment is indicated for the relief of the inflammatory manifestations of resistant or severe psoriasis and corticosteroid-responsive dermatoses.

DOSAGE AND ADMINISTRATION: A thin film of DIPROTOP Ointment should be applied to cover completely the affected area once daily, in the morning. DIPROTOP Ointment may also be applied twice daily, in the morning and at night, at the physician's discretion.

As with all highly active topical corticosteroid preparations, treatment shoud be discontinued when the dermatologic disorder is controlled. According to clinical response, duration of therapy may vary from a few days to a longer period of time. However, treatment should not be continued for more than four weeks without patient re-evaluation.

ADVERSE REACTIONS: The most frequent side effect reported is mild to moderate transient folliculitis (like acne) and is rare. Urticaria, increased redness of lesions, increased erythema, itching, vesiculation and pruritus have been reported.

Other local adverse reactions that have been reported with the use of topical corticosteroids include: burning, irritation, dryness, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae nad miliaria.

CONTRAINDICATIONS: DIPROTOP Ointment is contraindicated in those patients with a history of sensitivity reactions to betamethasone diproprionate, other corticosteroids or to any of the components of DIPROTOP Ointment.

 PRECAUTIONS: If irritation or sensitization develops with the use of DIPROTOP Ointment, treatment should be discontinued and appropriat therapy instituted.

In the presence of an infection, an appropriate antifungal or antibacterial agent should be administered. If a favorable response does not occur promptly, the corticosteroid should be discontinued until the infection has been controlled adequately.

Systemic absorption of topical corticosteroids will be increased if extensive body surface areas are treated which may interfere with the growth and development of children.

DIPROTOP Ointment is not intended for use under occlusive dressing since this will also increase systemic absorption of the corticosteroid.

DIPROTOP Ointment not for ophthalmic use

INSTRUCTION FOR PARENTS OF THE CHILDREN WITH PHIMOSIS : Apply and massage the phimotic skin with little amount of 0.05% betamethasone dipropionate ointment twice daily for 2 months. You should apply cream on foreskin especially most tight ring.  Stretching of tight foreskin (Phimosis) will be done before cream usage to achieve good result.